Effectiveness of Adjunct Sound Therapy with Al Qur'an Recitation (Surah Ruqyah) versus Fluoxetine in Patients with Depression: A Pilot Study

Authors

  • Sunandar Ihsan
  • halik halik UHO
  • Sugiyanto Sugiyanto
  • Soewadi Soewadi

DOI:

https://doi.org/10.24252/djps.v8i2.58334

Keywords:

Depression, Al Qur’an recitation, Surah ruqyah, , Sound therapy, BDI, Spirituality

Abstract

Introduction: Depression is a mental disorder that is widespread across various communities. The combination of non-pharmacological therapy is essential to enhance the efficacy of standard fluoxetine treatment. Previous studies demonstrate that non-pharmacological sound therapy utilizing al Qur’an recitation enhances mental health. Additionally, fluoxetine is associated with side effects, and combination therapy may elevate the risk of serious adverse events. Aims: The objective of this study is to assess the effectiveness of Qur'an recitation as an adjunctive therapy alongside standard fluoxetine treatment in depressed patients within psychiatric wards of government hospitals in Yogyakarta, Indonesia. Methods: This study is a pre-post control group design involving 21 hospitalized patients diagnosed with depression. Patients were categorized into two groups: 9 in the control group and 12 in the treatment group. The control group receives standard fluoxetine therapy, while the experimental group receives fluoxetine along with an additional 30 minutes of al Quran sound therapy daily for 14 days each morning. The Beck Depression Inventory was used to assess depression scores before and after the intervention, and an independent sample t-test was used for analysis. Result: The mean initial BDI scores were similar between the control group (26.89±3.82) and the treatment group (26.83±6.91). At the end of the treatment, the BDI scores for the control and treatment groups were 23.00±8.30 and 12.17±8.22, respectively. Both groups showed a decrease in mean BDI scores before and after therapy; however, the control group's mean score (3.89±6.99) was lower than that of the treatment group (14.67±8.30). The assessment results pre- and post-therapy indicated a significant difference in mean scores between the two groups, with a p-value of less than 0.05 (p = 0.005, mean = 10.77, 95% CI = 3.6 to 17.9).  Conclusion:  The addition of Quranic recitation sound therapy, namely Surah Ruqyah, to SSRI treatment (fluoxetine) showed a reduction of depression scores. In the Indonesian context, Quranic recitation sound therapy may serve as a non-pharmacological adjunct treatment for individuals with mental disorders, including depression.

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2025-12-28

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Ihsan, S., halik, halik, Sugiyanto, S., & Soewadi, S. (2025). Effectiveness of Adjunct Sound Therapy with Al Qur’an Recitation (Surah Ruqyah) versus Fluoxetine in Patients with Depression: A Pilot Study. Ad-Dawaa’ Journal of Pharmaceutical Sciences, 8(2), 191–208. https://doi.org/10.24252/djps.v8i2.58334

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