Formulation and Effectiveness Test of Centella Ethanol Extract (Centella asiatica (L) Urb) Serum as Skin Moisturizer
DOI:
https://doi.org/10.24252/djps.v8i2.57174Keywords:
Centella asiatica, serum, ethanol extract, skin moisturizer, skin hydration, stabilityAbstract
Introduction: Indonesia has a tropical climate that tends to have high temperature and humidity, leaving skin dry and vulnerable to damage from sun exposure and pollution. One potential natural solution is the use of Centella asiatica extract, which is known to have skin hydration, regeneration, and protection effects. Aims: This study aims to develop a stable Pegagan ethanol extract-based serum formulation and evaluate its effectiveness as a skin moisturizer. Methods: Serum formulation with various concentrations of Pegagan extract (1%, 5%, and 10%), extracted using 70% ethanol through maceration method. The resulting serum was tested for physical and chemical stability, as well as its effectiveness in improving skin hydration using a skin analyzer on panelists with comparisons to anegative control (base formulation) and a positive control (brand X serum). Tests were conducted to observe the parameters of pH, viscosity, homogeneity, spreadability, adhesiveness, and effectiveness of skin hydration after product use. Result: The study showed that the serum with 1% extract concentration (F1) had the best stability, with stable viscosity and pH that is suitable for human skin (pH 5). Statistically, there were no significant changes before and after stability testing. Effectiveness testing using the skin analyser revealed a 30-50% improvement in skin hydration after 6 days of serum application, indicating that Formula F1 is effective in increasing skin moisture. Meanwhile, serums with higher extract concentrations (F2 and F3) showed decreased viscosity and instability. Conclusion: The 1% Centella asiatica extract-based serum was proven to effectively enhance skin hydration and may serve as a promising alternative skin moisturizer.
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Ahmed Taher M. Mandal U. Jaffri J. Susanti D. Mahmood S. Zakaria Z., A. (2019). Pharmacological Properties of Centella asiatica Hydrogel in Accelerating Wound Healing in Rabbits. BMC Complementary and Alternative Medicine, 19(1). https://doi.org/10.1186/s12906-019-2625-2
An An S. Kang . Choe T. Lee S. Jang H. Bae S., I. (2012). Titrated Extract of Centella asiatica Provides a UVB Protective Effect by Altering Microrna Expression Profiles in Human Dermal Fibroblasts. International Journal of Molecular Medicine, 30(5), 1194–1202. https://doi.org/10.3892/ijmm.2012.1117
Febriani, Y., Handayani Lubis, S., & Annisa, F. (2019). Formulasi Sediaan Serum Ekstrak Daun Sirih Merah (Piper crocatum Ruiz & Pav.) sebagai Antioksidan Formulation of Red Betel Leaf Extract Serum (Piper crocatum Ruiz & Pav.) as Antioxidant. Journal of Pharmaceutical and Sciences.
Gandole, S. (2024). Formulation and Evaluation of Anti-acne Herbal Face Wash. International Journal of Science and Research Archive, 11(2), 1660–1667. https://doi.org/10.30574/ijsra.2024.11.2.0614
George Joseph L., M. (2010). Anti-allergic, Anti-pruritic, and Anti-inflammatory Activities of Centella asiatica Extracts. African Journal of Traditional Complementary and Alternative Medicines, 6(4). https://doi.org/10.4314/ajtcam.v6i4.57206
Maya, I., Sriwidodo, S., Mita, S. R., Kusumawulan, C. K., Putriana, N. A., Amalia, E., Aulia, R. N., Sofyan, H. N., Dzulfannazhir, F., & Nugraha, M. H. (2024). Formulation and Evaluation of Facial Serum Containing Sacha Inchi Oil (Plukenetia volubilis L.) from Indonesia as an Anti-Aging: Stability, In Vitro, and Skin Irritation Assessments. Cosmetics, 11(6), 226. https://doi.org/10.3390/cosmetics11060226
Novika, K. H., Chaerunissa, A. Y., Sriwidodo, S., & Annissya, W. P. (2024). Journal Review: Formulation and Evaluation of Anti-Oxidant Facial Serum and From Extracts of Various Plants. Eduvest - Journal of Universal Studies, 4(12), 11353–11361. https://doi.org/10.59188/eduvest.v4i12.50059
Pratiwi Fudholi A. Martien R. Pramono S., L. (2017). Self-nanoemulsifying Drug Delivery System (SNDDS) for Topical Delivery of Mangosteen Peels (garcinia mangostana l.,): formulation design and in vitro studies. Journal of Young Pharmacists, 9(3), 341–346. https://doi.org/10.5530/jyp.2017.9.68
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